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1

Cantilever Sensor for Nanomechanical Detection of Specific Protein Conformations

Mukhopadhyay, Rupa, Sumbayev, Vadim V., Lorentzen, Martin, Kjems, Jørgen, Andreasen, Peter A., Besenbacher, Flemming

Journal:

Year:

2005

Language:

english

File:

PDF, 119 KB

english, 2005

2

Mitochondrial Defunctionalization Supresses Tim-3-Galectin-9 Secretory Pathway in Human Colorectal Cancer Cells and Thus Can Possibly Affect Tumor Immune Escape

Sakhnevych, Svetlana S., Yasinska, Inna M., Fasler-Kan, Elizaveta, Sumbayev, Vadim V.

Journal:

Frontiers in Pharmacology

Year:

2019

Language:

english

File:

PDF, 1.91 MB

english, 2019

3

Apoptosis signal-regulating kinase 1 (ASK1) and HIF-1α protein are essential factors for nitric oxide-dependent accumulation of p53 in THP-1 human myeloid macrophages

Mohammad Jawahir, Sally A. Nicholas, Karen Coughlan, Vadim V. Sumbayev

Journal:

Year:

2008

Language:

english

File:

PDF, 326 KB

english, 2008

4

Involvement of hypoxia-inducible factor-1 HiF(1α) in IgE-mediated primary human basophil responses

Vadim V. Sumbayev, Sally A. Nicholas, Claire L. Streatfield, Bernhard F. Gibbs

Journal:

European Journal of Immunology

Year:

2009

Language:

english

File:

PDF, 313 KB

english, 2009

5

PI3 kinase and direct S-nitrosation are involved in down-regulation of apoptosis signal-regulating kinase 1 during LPS-induced Toll-like receptor 4 signalling

Vadim V. Sumbayev

Journal:

Immunology Letters

Year:

2008

Language:

english

File:

PDF, 363 KB

english, 2008

6

Hypoxia-inducible Factor 1 as one of the “Signaling Drivers” of Toll-like Receptor-Dependent and Allergic Inflammation

Vadim V. Sumbayev, Sally A. Nicholas

Journal:

Archivum Immunologiae et Therapiae Experimentalis

Year:

2010

Language:

english

File:

PDF, 310 KB

english, 2010

7

Involvement of xanthine oxidase and hypoxia-inducible factor 1 in Toll-like receptor 7/8-mediated activation of caspase 1 and interleukin-1β

Sally A. Nicholas, Vladimir V. Bubnov, Inna M. Yasinska, Vadim V. Sumbayev

Journal:

Cellular and Molecular Life Sciences

Year:

2011

Language:

english

File:

PDF, 513 KB

english, 2011

8

The involvement of hypoxia-inducible factor 1 alpha in Toll-like receptor 7/8-mediated inflammatory response

Sumbayev, Vadim V, Nicholas, Sally A

Journal:

Year:

2009

Language:

english

File:

PDF, 752 KB

english, 2009

9

The role of redox-dependent mechanisms in the downregulation of ligand-induced Toll-like receptors 7, 8 and 4-mediated HIF-1α prolyl hydroxylation

Nicholas, Sally A, Sumbayev, Vadim V

Journal:

Immunology & Cell Biology

Year:

2009

Language:

english

File:

PDF, 479 KB

english, 2009

10

The involvement of sphingosine kinase 1 in LPS-induced Toll-like receptor 4-mediated accumulation of HIF-1α protein, activation of ASK1 and production of the pro-inflammatory cytokine IL-6

Pitson, Stuart M, Waxman, Jonathan, Sumbayev, Vadim V, Pchejetski, Dmitri, Nunes, Joao, Coughlan, Karen, Lall, Harjinder

Journal:

Immunology & Cell Biology

Year:

2010

Language:

english

File:

PDF, 489 KB

english, 2010

11

Azinomycin epoxide induces activation of apoptosis signal-regulating kinase 1 (ASK1) and caspase 3 in a HIF-1α-independent manner in human leukaemia myeloid macrophages

Maxwell A. Casely-Hayford, Sally A. Nicholas, Vadim V. Sumbayev

Journal:

European Journal of Pharmacology

Year:

2009

Language:

english

File:

PDF, 683 KB

english, 2009

12

LPS-induced Toll-like receptor 4 signalling triggers cross-talk of apoptosis signal-regulating kinase 1 (ASK1) and HIF-1α protein

Vadim V. Sumbayev

Journal:

Year:

2008

Language:

english

File:

PDF, 700 KB

english, 2008

13

Myeloid cell death associated with Toll-like receptor 7/8-mediated inflammatory response. Implication of ASK1, HIF-1alpha, IL-1beta and TNF-alpha

Sally A. Nicholas, Abraham E. Oniku, Vadim V. Sumbayev

Journal:

Molecular Immunology

Year:

2010

Language:

english

File:

PDF, 774 KB

english, 2010

14

Mesangial cells but not hepatocytes are protected against NO/O2− cogeneration: mechanistic considerations

Vadim V. Sumbayev, Katrin B. Sandau, Bernhard Brüne

Journal:

European Journal of Pharmacology

Year:

2002

Language:

english

File:

PDF, 279 KB

english, 2002

15

S-Nitrosation of thioredoxin in the nitrogen monoxide/superoxide system activates apoptosis signal-regulating kinase 1

Inna M Yasinska, Anna V Kozhukhar, Vadim V Sumbayev

Journal:

Archives of Biochemistry and Biophysics

Year:

2004

Language:

english

File:

PDF, 263 KB

english, 2004

16

Regulation of MAP kinase-dependent apoptotic pathway: implication of reactive oxygen and nitrogen species

Vadim V. Sumbayev, Inna M. Yasinska

Journal:

Archives of Biochemistry and Biophysics

Year:

2005

Language:

english

File:

PDF, 449 KB

english, 2005

17

Dysfunctional mitochondria contain endogenous high-affinity human Toll-like receptor 4 (TLR4) ligands and induce TLR4-mediated inflammatory reactions

Sally A. Nicholas, Karen Coughlan, Inna Yasinska, Gurprit S. Lall, Bernhard F. Gibbs, Luigi Calzolai, Vadim V. Sumbayev

Journal:

The International Journal of Biochemistry & Cell Biology

Year:

2011

Language:

english

File:

PDF, 966 KB

english, 2011

18

Nitric oxide inhibits HIF-1α protein accumulation under hypoxic conditions: implication of 2-oxoglutarate and iron

Anna V. Kozhukhar, Inna M. Yasinska, Vadim V. Sumbayev

Journal:

Year:

2006

Language:

english

File:

PDF, 565 KB

english, 2006

19

A novel pesticide-induced conformational state of the oestrogen receptor ligand-binding domain, detected by conformation-specific peptide binding

Vadim V. Sumbayev, Eva C. Bonefeld-Jørgensen, Troels Wind, Peter A. Andreasen

Journal:

Year:

2005

Language:

english

File:

PDF, 316 KB

english, 2005

20

Novel modes of oestrogen receptor agonism and antagonism by hydroxylated and chlorinated biphenyls, revealed by conformation-specific peptide recognition patterns

Vadim V. Sumbayev, Jan K. Jensen, Jacob A. Hansen, Peter A. Andreasen

Journal:

Molecular and Cellular Endocrinology

Year:

2008

Language:

english

File:

PDF, 1.15 MB

english, 2008

21

HIF-1α protein is an essential factor for protection of myeloid cells against LPS-induced depletion of ATP and apoptosis that supports Toll-like receptor 4-mediated production of IL-6

Harjinder Lall, Karen Coughlan, Vadim V. Sumbayev

Journal:

Molecular Immunology

Year:

2008

Language:

english

File:

PDF, 453 KB

english, 2008

22

S-nitrosylation of thioredoxin mediates activation of apoptosis signal-regulating kinase 1

Vadim V Sumbayev

Journal:

Archives of Biochemistry and Biophysics

Year:

2003

Language:

english

File:

PDF, 216 KB

english, 2003

23

HIF-1α protein as a target for S-nitrosation

Vadim V Sumbayev, Andreja Budde, Jie Zhou, Bernhard Brüne

Journal:

Year:

2003

Language:

english

File:

PDF, 248 KB

english, 2003

24

S-nitrosation of Cys-800 of HIF-1α protein activates its interaction with p300 and stimulates its transcriptional activity

Inna M Yasinska, Vadim V Sumbayev

Journal:

Year:

2003

Language:

english

File:

PDF, 203 KB

english, 2003

25

Differential control of hypoxia-inducible factor 1 activity during pro-inflammatory reactions of human haematopoietic cells of myeloid lineage

Gibbs, Bernhard F., Yasinska, Inna M., Pchejetski, Dmitri, Wyszynski, Rafal W., Sumbayev, Vadim V.

Journal:

The International Journal of Biochemistry & Cell Biology

Year:

2012

Language:

english

File:

PDF, 1.43 MB

english, 2012

26

Microscopic Analysis of the Interaction of Gold Nanoparticles with Cells of the Innate Immune System

García, César Pascual, Sumbayev, Vadim, Gilliland, Douglas, Yasinska, Inna M., Gibbs, Bernhard F., Mehn, Dora, Calzolai, Luigi, Rossi, François

Journal:

Scientific Reports

Year:

2013

Language:

english

File:

PDF, 918 KB

english, 2013

27

An Electrochemical Sensor Based on the Human Estrogen Receptor Ligand Binding Domain

Hansen, Jacob A., Sumbayev, Vadim V., Gothelf, Kurt V.

Journal:

Year:

2007

Language:

english

File:

PDF, 115 KB

english, 2007

28

Interleukin-1 beta induces the expression and production of stem cell factor by epithelial cells: crucial involvement of the PI-3K/mTOR pathway and HIF-1 transcription complex

Wyszynski, Rafal W, Gibbs, Bernhard F, Varani, Luca, Iannotta, Daniela, Sumbayev, Vadim V

Journal:

Cellular & Molecular Immunology

Year:

2014

Language:

english

File:

PDF, 2.37 MB

english, 2014

29

Peroxynitrite as an alternative donor of oxygen in HIF-1α proline hydroxylation under low oxygen availability

Sumbayev, Vadim V., Yasinska, Inna M.

Journal:

Free Radical Research

Year:

2006

Language:

english

File:

PDF, 200 KB

english, 2006

30

Gold Nanoparticles Downregulate Interleukin-1β-Induced Pro-Inflammatory Responses

Sumbayev, Vadim V., Yasinska, Inna M., Garcia, Cesar Pascual, Gilliland, Douglas, Lall, Gurprit S., Gibbs, Bernhard F., Bonsall, David R., Varani, Luca, Rossi, François, Calzolai, Luigi

Journal:

Year:

2013

Language:

english

File:

PDF, 637 KB

english, 2013

31

The immune receptor Tim-3 mediates activation of PI3 kinase/mTOR and HIF-1 pathways in human myeloid leukaemia cells

Prokhorov, Alexandr, Gibbs, Bernhard F., Bardelli, Marco, Rüegg, Laura, Fasler-Kan, Elizaveta, Varani, Luca, Sumbayev, Vadim V.

Journal:

The International Journal of Biochemistry & Cell Biology

Year:

2015

Language:

english

File:

PDF, 2.33 MB

english, 2015

32

[Methods in Enzymology] Nitric Oxide, Part F Volume 440 || Protein S‐Nitrosation in Signal Transduction: Assays for Specific Qualitative and Quantitative Analysis

Sumbayev, Vadim V.

Year:

2008

Language:

english

File:

PDF, 152 KB

english, 2008

33

Highly Specific Targeting of Human Leukocytes Using Gold Nanoparticle-Based Biologically Active Conjugates

Gibbs, Bernhard F., Yasinska, Inna M., Calzolai, Luigi, Gilliland, Douglas, Sumbayev, Vadim V.

Journal:

Journal of Biomedical Nanotechnology

Year:

2014

Language:

english

File:

PDF, 8.39 MB

english, 2014

34

The role of basophils in allergic inflammation

Raap, Ulrike, Sumbayev, Vadim V., Gibbs, Bernhard F.

Journal:

Allergo Journal

Year:

2015

Language:

english

File:

PDF, 365 KB

english, 2015

35

The role of basophils in allergic inflammation

Raap, Ulrike, Sumbayev, Vadim V., Gibbs, Bernhard F.

Journal:

Allergo Journal International

Year:

2015

Language:

english

File:

PDF, 366 KB

english, 2015

36

129 Involvement of the Hypoxia-Inducible Factor-1 Transcription Complex in the Inflammatory Responses of Human Mast Cells and Basophils

Yasinska, Inna, Sumbayev, Vadim, Gibbs, Bernhard

Journal:

World Allergy Organization Journal

Year:

2012

Language:

english

File:

PDF, 82 KB

english, 2012

37

61 Hypoxia-Inducible Factor 1 (HIF-1) Transcription is a “Signalling Driver” for Allergic Inflammation, Host Innate Immune Defence and Leukaemia Progression

Sumbayev, Vadim, Yasinska, Inna, Gibbs, Bernhard

Journal:

World Allergy Organization Journal

Year:

2012

Language:

english

File:

PDF, 99 KB

english, 2012

38

The immune receptor Tim-3 acts as a trafficker in a Tim-3/galectin-9 autocrine loop in human myeloid leukemia cells

Gonçalves Silva, Isabel, Rüegg, Laura, Gibbs, Bernhard F., Bardelli, Marco, Fruewirth, Alexander, Varani, Luca, Berger, Steffen M., Fasler-Kan, Elizaveta, Sumbayev, Vadim V.

Journal:

Year:

2016

Language:

english

File:

PDF, 2.14 MB

english, 2016

39

Crucial involvement of xanthine oxidase in the intracellular signalling networks associated with human myeloid cell function

Abooali, Maryam, Lall, Gurprit S., Coughlan, Karen, Lall, Harjinder S., Gibbs, Bernhard F., Sumbayev, Vadim V.

Journal:

Scientific Reports

Year:

2014

Language:

english

File:

PDF, 1.07 MB

english, 2014

40

Differential Role of Hypoxia-Inducible Factor 1 Alpha in Toll-Like Receptor-Mediated and Allergic Inflammatory Reactions

Vadim V. Sumbayev PhD,Sally A. Nicholas PhD…

Journal:

World Allergy Organization Journal

Year:

2010

Language:

english

File:

PDF, 325 KB

english, 2010

41

Biochemical mechanisms implemented by human acute myeloid leukemia cells to suppress host immune surveillance

Yasinska, Inna M., Gonçalves Silva, Isabel, Sakhnevych, Svetlana, Gibbs, Bernhard F., Raap, Ulrike, Fasler-Kan, Elizaveta, Sumbayev, Vadim V.

Journal:

Cellular & Molecular Immunology

Year:

2018

Language:

english

File:

PDF, 483 KB

english, 2018

42

Effects of Stem Cell Factor on Hypoxia-Inducible Factor 1 Alpha Accumulation in Human Acute Myeloid Leukaemia and LAD2 Mast Cells

Gibbs, Bernhard F., Yasinska, Inna M., Oniku, Abraham E., Sumbayev, Vadim V., Sozzani, Silvano

Journal:

Year:

2011

Language:

english

File:

PDF, 560 KB

english, 2011

43

Expression of functional neuronal receptor latrophilin 1 in human acute myeloid leukaemia cells

Sumbayev, Vadim V., Silva, Isabel Gonçalves, Blackburn, Jennifer, Gibbs, Bernhard F., Yasinska, Inna M., Garrett, Michelle D., Tonevitsky, Alexander G., Ushkaryov, Yuri A.

Journal:

Year:

2016

Language:

english

File:

PDF, 6.49 MB

english, 2016

44

Expression of functional neuronal receptor latrophilin 1 in human acute myeloid leukaemia cells

Sumbayev, Vadim V., Silva, Isabel Gonçalves, Blackburn, Jennifer, Gibbs, Bernhard F., Yasinska, Inna M., Garrett, Michelle D., Tonevitsky, Alexander G., Ushkaryov, Yuri A.

Journal:

Year:

2016

File:

PDF, 6.49 MB

2016

45

Editorial: The Challenge of New Therapeutic Approaches for Unmet Therapeutic Needs

Rosa, Arianna Carolina, Mio, Mitsunobu, Andreadou, Ioanna, Sumbayev, Vadim V.

Journal:

Frontiers in Pharmacology

Year:

2020

File:

PDF, 218 KB

2020